Pathogen adaptation to seasonal forcing and climate change.

  title={Pathogen adaptation to seasonal forcing and climate change.},
  author={Katia Koelle and Mercedes Pascual and Mohammad Yunus},
  journal={Proceedings. Biological sciences},
  volume={272 1566},
Many diverse infectious diseases exhibit seasonal dynamics. Seasonality in disease incidence has been attributed to seasonal changes in pathogen transmission rates, resulting from fluctuations in extrinsic climate factors. Multi-strain infectious diseases with strain-specific seasonal signatures, such as cholera, indicate that a range of seasonal patterns in transmission rates is possible in identical environments. We therefore consider pathogens capable of evolving their 'seasonal phenotype… CONTINUE READING


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