Pathogen Recognition by the Innate Immune System

@article{Kumar2011PathogenRB,
  title={Pathogen Recognition by the Innate Immune System},
  author={Himanshu Kumar and Taro Kawai and Shizuo Akira},
  journal={International Reviews of Immunology},
  year={2011},
  volume={30},
  pages={16 - 34}
}
Microbial infection initiates complex interactions between the pathogen and the host. Pathogens express several signature molecules, known as pathogen-associated molecular patterns (PAMPs), which are essential for survival and pathogenicity. PAMPs are sensed by evolutionarily conserved, germline-encoded host sensors known as pathogen recognition receptors (PRRs). Recognition of PAMPs by PRRs rapidly triggers an array of anti-microbial immune responses through the induction of various… Expand
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