Pathobiology of oral mucositis: novel insights and opportunities.

  title={Pathobiology of oral mucositis: novel insights and opportunities.},
  author={Stephen T. Sonis},
  journal={The journal of supportive oncology},
  volume={5 9 Suppl 4},
Oral mucositis is a common and debilitatingly painful side effect of many forms of chemotherapy and radiation therapy. The erythematous, atrophic, and ulcerative lesions that develop are a consequence of epithelial damage and death mediated through a complex series of molecular and cellular events. The consequences of mucositis are far-reaching and include chemotherapy dose reductions, breaks in radiation treatment, cessation of cancer therapy, reliance on parenteral nutrition, administration… CONTINUE READING