Pathfinder selection: in situ isolation of novel antibodies.

Abstract

BACKGROUND To devise a novel method for targeted recovery of binding molecules from phage libraries. OBJECTIVES To assess the potential of the novel technique to the selection of human antibodies to specific cell surface antigens in situ, including carcinoembryonic antigen (CEA), E- and P-selectins, and to the selection of novel antibodies which recognize… (More)

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