Paternal nicotine exposure alters hepatic xenobiotic metabolism in offspring

Abstract

Paternal environmental conditions can influence phenotypes in future generations, but it is unclear whether offspring phenotypes represent specific responses to particular aspects of the paternal exposure history, or a generic response to paternal 'quality of life'. Here, we establish a paternal effect model based on nicotine exposure in mice, enabling… (More)
DOI: 10.7554/eLife.24771

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