Paternal monoallelic expression of PEG3 in the human placenta.

  title={Paternal monoallelic expression of PEG3 in the human placenta.},
  author={Susan E. Hiby and Marvin D. Lough and Eric B. Keverne and M. Azim Surani and Yung Wai Loke and Alan King},
  journal={Human molecular genetics},
  volume={10 10},
Genomic imprinting is the phenomenon whereby mono-allelic expression of certain genes occurs depending on their parental origin. The observation that imprinting only occurs in placental mammals has led to the suggestion that it may play a role in this form of reproduction. In the present study we have investigated the pattern of expression of the human PEG3 gene in the early to term placenta, as well as the uterus and ovary, using RT-PCR, northern blot and in situ hybridization. A comparison is… CONTINUE READING
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