Paternal line multigenerational passage of altered risk assessment behavior in female but not male rat offspring of mothers fed a low protein diet.

@article{ReyesCastro2015PaternalLM,
  title={Paternal line multigenerational passage of altered risk assessment behavior in female but not male rat offspring of mothers fed a low protein diet.},
  author={Luis A Reyes-Castro and Guadalupe L. Rodr{\'i}guez-Gonz{\'a}lez and Roberto Chavira and Carlos A. Ib{\'a}{\~n}ez and Consuelo Lomas-Soria and Jesse S. Rodriguez and Peter W Nathanielsz and Elena Zambrano},
  journal={Physiology & behavior},
  year={2015},
  volume={140},
  pages={89-95}
}
Maternal low protein (MLP) diets in pregnancy and lactation impair offspring brain development and modify offspring behavior. We hypothesized multigenerational passage of altered behavioral outcomes as has been demonstrated following other developmental programming challenges. We investigated potential multigenerational effects of MLP in rat pregnancy and/or lactation on offspring risk assessment behavior. Founder generation mothers (F0) ate 20% casein (C) or restricted (R) 10% casein diet… CONTINUE READING