• DOI:10.1038/352255A0
Corpus ID: 4278149

Paternal inheritance of mitochondrial DNA in mice

@article{Gyllensten1991PaternalIO,
  title={Paternal inheritance of mitochondrial DNA in mice},
  author={U. Gyllensten and D. Wharton and Agneta Josefsson and A. C. Wilson},
  journal={Nature},
  year={1991},
  volume={352},
  pages={255-257}
}

U. Gyllensten, D. Wharton, +1 author A. C. Wilson

Published 1991

Biology, Medicine

Nature

FOR nearly 20 years it has been assumed on the basis of low-resolution experiments that mitochondrial (mt)DNA, in contrast to the genes in the nucleus, has an exclusively maternal mode of inheritance in animals1. Using the polymerase chain reaction2, 3, paternally inherited mtDNA molecules have now been detected in mice at a frequency of 10−4, relative to the maternal contributions. These mice were hybrids between two inbred strains (C57BL/6J and Mus spretus) whose mtDNAs can be distinguished… CONTINUE READING

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