Patent foramen ovale closure versus medical therapy in cases with cryptogenic stroke, meta-analysis of randomized controlled trials

@article{Abosalem2018PatentFO,
  title={Patent foramen ovale closure versus medical therapy in cases with cryptogenic stroke, meta-analysis of randomized controlled trials},
  author={Elsayed Abo-salem and Bernard R. Chaitman and Tarek Helmy and Eric Adjei Boakye and Hassan Alkhawam and Michael B Lim},
  journal={Journal of Neurology},
  year={2018},
  volume={265},
  pages={578-585}
}
PFO is more common in cases with cryptogenic stroke compared to cases with no stroke or stroke of identified etiology. Several randomized controlled trials (RCTs) comparing PFO closure with medical therapy have been published with controversial findings. PubMed, Embase and Cochrane library databases were searched for RCT comparing PFO closure with medical… CONTINUE READING