Patent ductus arteriosus and indomethacin treatment as independent risk factors for plus disease in retinopathy of prematurity.

@article{Tsui2013PatentDA,
  title={Patent ductus arteriosus and indomethacin treatment as independent risk factors for plus disease in retinopathy of prematurity.},
  author={Irena Tsui and E J Ebani and Jamie B. Rosenberg and Juan Lin and Robert M. Angert and Umar K. Mian},
  journal={Journal of pediatric ophthalmology and strabismus},
  year={2013},
  volume={50 2},
  pages={
          88-92
        }
}
  • I. Tsui, E. Ebani, +3 authors U. Mian
  • Published 15 January 2013
  • Medicine
  • Journal of pediatric ophthalmology and strabismus
PURPOSE To examine whether clinically significant patent ductus arteriosus (PDA) or indomethacin treatment are associated with plus disease or retinopathy of prematurity (ROP) requiring treatment. METHODS Retrospective, cross-sectional study. Charts were reviewed for gestational age, birth weight, birth head circumference, birth length, maternal characteristics, gender, bronchopulmonary dysplasia, neurologic comorbidities, PDA and its treatments, gastrointestinal comorbidities, blood… 
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High Dose Indomethacin for Patent Ductus Arteriosus Closure Increases Neonatal Morbidity.
TLDR
HDI used for PDA closure is associated with an increase in necrotizing enterocolitis and BPD, and risks of HDI should be balanced against other treatment options.
Patent Ductus Arteriosus Ligation and Adverse Outcomes: Causality or Bias?
TLDR
Increased mortality and CLD in infants with persistent symptomatic PDA suggests that surgical ligation remains an important treatment modality for preterm infants and a period of conservative management after failure of medical PDA closure may be considered to reduce the number of infants treated with surgery.
Duration of significant patent ductus arteriosus and bronchopulmonary dysplasia in extremely preterm infants
TLDR
Logistic regression analysis showed that longer duration of significant PDA was associated with higher risk for death or BPD (adjusted OR 1.37, 95% CI 1.03–1.82).Longer duration ofsignificant PDA is associated with theHigher risk for BPD/death in extremely preterm infants.
Association between Hemodynamically Significant Patent Ductus Arteriosus and Bronchopulmonary Dysplasia.
PDA Ligation and Health Outcomes: A Meta-analysis
TLDR
Surgical ligation of PDA is associated with reduced mortality, but surviving infants are at increased risk of NDI, however, there is a lack of studies addressing survival bias and confounding by indication.
Early targeted patent ductus arteriosus treatment in premature neonates using a risk based severity score: study protocol for a randomised controlled trial (PDA RCT)
TLDR
It is hypothesised that in preterm infants at high risk of developing CLD/Death based on a PDAsc, early treatment with Ibuprofen compared with placebo will result in a reduction in CLD /Death.
Retinopathy of prematurity: Risk factors and variability in Canadian neonatal intensive care units.
TLDR
Younger, smaller and sicker male infants had higher adjusted risks of severe ROP and rates varied significantly among sites, as well as between sites.
Fluid Intake in the First Week of Life and the Duration of Hemodynamically Significant Patent Ductus Arteriosus in Extremely Preterm Infants.
TLDR
In extremely preterm infants, higher fluid intake in first 2 days of life is associated with prolonged duration of hsPDA, and actual daily fluid intake can be significantly higher than prescribed daily fluids due to daily weight changes and additional fluid administration.
Incidence and factors predisposing to retinopathy of prematurity in inborn infants less than 32 weeks of gestation.
TLDR
The study confirmed the importance of birth weight as an independent ROP risk factor and showed that Sepsis, NEC, PDA, and prolonged mechanical ventilation have been shown to be independent risk factors in the different gestational age groups.
Retinopathy of Prematurity Among Very Low-Birth-Weight Infants in China: Incidence and Perinatal Risk Factors.
TLDR
In VLBW Chinese infants, IVF, GA < 32 weeks, apnea, BPD, sepsis, PDA, and blood transfusion were independent perinatal risk factors for ROP.
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TLDR
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TLDR
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