Patent Toxocara canis infections in previously exposed and in helminth-free dogs after infection with low numbers of embryonated eggs.

@article{Fahrion2008PatentTC,
  title={Patent Toxocara canis infections in previously exposed and in helminth-free dogs after infection with low numbers of embryonated eggs.},
  author={Anna Fahrion and Sandra Staebler and Peter Deplazes},
  journal={Veterinary parasitology},
  year={2008},
  volume={152 1-2},
  pages={
          108-15
        }
}
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61 Citations
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27
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6
Results Citations
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A critical reflection on current control of Toxocara canis in household dogs
TLDR
A major finding was that a minority of ‘wormy animals’ was found to be responsible for the majority of the positive samples containing Toxocara eggs, and targeted treatment of these ‘wormsy dogs’ might be more efficient in reducing the household dogs” contribution to the environmental contamination with roundworm eggs than blind deworming of all household dogs.
[Toxocarosis in dogs - important aspects for the veterinary practice].
TLDR
Based on the zoonotic potential, information concerning the biology of the parasite and the necessity of anthelmintic treatment to effectively control T. canis in dogs should be provided for the pet owner to lead to better parasite control and decreased environmental contamination.
Efficacy of milbemycin oxime in combination with spinosad in the treatment of larval and immature adult stages of Ancylostoma caninum and Toxocara canis in experimentally infected dogs.
The hamster (Mesocricetus auratus) as an experimental model of toxocariasis: histopathological, immunohistochemical, and immunoelectron microscopic findings
TLDR
The hamster model displayed a progressive rise of anti-toxocaral antibodies with the formation of immune complexes and Lung and liver manifestations of toxocariasis in hamsters approximated those in humans and other experimental animal models.
Larval development of Toxocara canis in dogs.
Recurrent patent infections with Toxocara canis in household dogs older than six months: a prospective study
TLDR
Targeted anthelmintic treatments in household dogs may be feasible as PIs tend to (re)occur in specific periods and in groups of dogs at high risk.
Coprological survey of endoparasite infections in owned dogs and owners' perceptions of endoparasite control in Belgium and the Netherlands.
Endoparasite prevalence and recurrence across different age groups of dogs and cats.
Longitudinal study for anthelmintic efficacy against intestinal helminths in naturally exposed Lithuanian village dogs: critical analysis of feasibility and limitations
TLDR
A critical analyses of factors possibly responsible for intestinal passage of canine helminth eggs revealed that chained dogs excreted T. canis eggs more frequently 1 month after treatment compared to dogs in pens, particularly from November to March.
Effectiveness of Credelio® Plus, a novel chewable tablet containing milbemycin oxime and lotilaner for the treatment of larval and immature adult stages of Toxocara canis in experimentally infected dogs
TLDR
Two randomized, blinded, GCP-compliant, pivotal laboratory dose confirmation studies demonstrated that the Credelio Plus combination tablet administered orally to dogs was highly efficacious against experimental infections with L4 and immature adult [L5] Stage T. canis.
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The findings imply that adult dogs may not always be immune to toxocaral infection and may therefore contribute significantly to the problem of environmental contamination with T. canis ova.
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It is concluded that education on the life cycles of the parasites, hygiene, and anthelmintic treatment schedules is required because of the zoonotic risks of Toxocara spp.
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The effect of feeding different numbers of Toxocara canis eggs on patent intestinal infections was studied in 45 ascarid-naive 62--64-day-old pups and 6 adult dogs. Twenty-four of 25 pups fed 10 to…
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The increased susceptibility to infection with T. canis in the dog treated with high doses of corticosteroids was associated with a decrease in in vitro lymphocyte responsiveness to the mitogens concanavalin A and pokeweed mitogen and with a complete suppression of the eosinophilia that was seen 10 days after infection in the untreated control dog.
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Superinfection of naturally infected puppies with large numbers of Toxocara canis eggs induced a self-cure reaction, and acquired resistance reduced the pathogenic effects of superinfection, and prevented development of the parasite beyond the second stage.
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