Patency of the infarct-related coronary artery and ventricular geometry.

@article{Lamas1991PatencyOT,
  title={Patency of the infarct-related coronary artery and ventricular geometry.},
  author={Gervasio A. Lamas and Marc Pfeffer and Eugene Braunwald},
  journal={The American journal of cardiology},
  year={1991},
  volume={68 14},
  pages={41D-51D}
}
The pathogenesis of acute myocardial infarction (AMI) involves a sudden thrombotic occlusion of a coronary artery. Spontaneous or pharmacologic thrombolysis may lead to myocardial salvage if patency is achieved within a narrow time window. However, patients in whom thrombolysis occurs late seem to demonstrate improved left ventricular (LV) function and prognosis, which may be independent of myocardial salvage. Preservation of normal LV geometry by reducing expansion of the infarcted segment is… CONTINUE READING

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