Patchwork women

  title={Patchwork women},
  author={Carolyn Brown},
  journal={Nature Genetics},
If humans had an X-linked biallelic coat color gene, as cats do, then female mosaicism would be as evident in humans as it is in calico cats. This outcome of X inactivation is not immediately visible in humans, however, and its potential importance in sex differences in disease is often overlooked. In the introduction to Females are Mosaics, Barbara Migeon states she has been “surprised by the small impact this subject has had in medicine.” This book sets out to remedy this deficiency by…