Patch testing with fragrances: results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes

  title={Patch testing with fragrances: results of a multicenter study of the European Environmental and Contact Dermatitis Research Group with 48 frequently used constituents of perfumes},
  author={Peter J Frosch and Beate Pilz and Klaus Ejner Andersen and Desmond Burrows and Jos{\'e} G. Camarasa and A. Dooms‐goossens and Georges Ducombs and Th. Fuchs and M. Hannusksela and J. M. Lachapelle and Arto Lahti and Howard I Maibach and Torkil Menn{\'e} and Richard J. G. Rycroft and Stephanie Shaw and Jan E. Wahlberg and Ian R. White and John D. Wilkinson},
  journal={Contact Dermatitis},
The objective of this study was to determine the frequency of reactivity to a series of commonly fragrances in dermatological patients. A total of 48 fragrances (FF) were chosen, based on the publication of Fenn in 1989 in which the lop 25 constituents of 3 types (1. perfumes, 2. household products, 3. soaps) of 400 commercial products on the US market had been determined. In a pilot study on a total of 1069 patients in 11 centres, the appropriate test concentration and vehicle were examined… 

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