Patch testing of patients allergic to Disperse Blue 106 and Disperse Blue 124 with thin‐layer chromatograms and purified dyes

  title={Patch testing of patients allergic to Disperse Blue 106 and Disperse Blue 124 with thin‐layer chromatograms and purified dyes},
  author={Kristina Ryberg and An Goossens and Marl{\'e}ne Isaksson and Birgitta Gruvberger and Erik Zimerson and Lena Persson and Magnus Bruze},
  journal={Contact Dermatitis},
Background:  Former investigations have demonstrated that patch test preparations containing Disperse Blue (DB) 106 and DB 124 are impure. 
Patch testing with a textile dye mix – a multicentre study
Disperse dyes are well‐known contact sensitizers. However, they are not included in the majority of commercially available baseline patch test series.
Contact allergy from disperse dyes in textiles–a review
Several disperse dyes are still considered to be the most important allergens in textile dermatitis, but there are sparse data about their current use in textiles, and it is necessary to check the purity and identity of dyes used for patch testing, confirm the clinical relevance of positive reactions by patch testing with suspected textile, and determine the culprit dye. Expand
Textile Dyes Disperse Orange 1 and Yellow 3 Contain More Than One Allergen As Shown by Patch Testing with Thin‐Layer Chromatograms
The results of this study suggest that there are more relevant allergens in the fat‐soluble and water-soluble fractions of the commercial disperse dyes. Expand
Patch Testing To a Textile Dye Mix by the International Contact Dermatitis Research Group
Over 30% of the TDM allergic patients had been missed if only the international baseline series was tested, suggesting contact allergy to TDM could explain or contribute to dermatitis in over 20% of of the patients. Expand
Sensitizing capacity of Disperse Orange 1 and its potential metabolites from azo reduction and their cross‐reactivity pattern
Some metabolites from the azo reduction of these disperse azo dyes could be sensitizers, as human skin bacteria produce azo reductases. Expand
Clinical and epidemiological features of textile contact dermatitis:an Italian multicentre study
The prevalence of occupational and non‐occupational textile dermatitis seems to be increasing, probably because of changed textile manufacturing techniques.
Contact allergy to textile dyes: Clinical and experimental studies on disperse azo dyes
Disperse dyes are the most common allergens among textile dyes. It is not known whether the purified dyes, impurities in the commercial dyes, or metabolites are the actual sensitisers. Moreover, itExpand
Patch testing with a textile dye mix in two concentrations - a multicentre study by the Swedish contact dermatitis research group.
Investigation of patch-testing with a textile dye mix (TDM) at 7 dermatology clinics in Sweden found contact allergy to the TDM is common and inclusion into the Swedish baseline series should be considered. Expand
Allergic Contact Dermatitis to p-phenylenediamine and Some of its Reaction Products
Background Contact allergy to hair dyes is prevalent among hairdressers and their consumers. The potent sensitizer p-phenylenediamine (PPD) is a common colour substance in oxidizing permanent hairExpand
Contact sensitization to textile dyes in a self‐selected population and a dermatological referral population in Beijing
The purpose of this study was to determine the prevalence of contact sensitization to textile dyes in a non-patient population and in eczema patients patch tested in a tertiary hospital in Beijing. Expand


Chemical investigations of disperse dyes in patch test preparations
This data indicates that contact allergy to textile dyes is not uncommon and can be detected by patch testing patients with commercial patch test preparations. Expand
Risks and possibilities in patch testing with contaminated personal objects: usefulness of thin‐layer chromatograms in a patient with acrylate contact allergy from a chemical burn
We report a case of a chemical burn from dipropylene glycol diacrylate (DPGDA) spilt on working shoes, followed by active sensitization, thus giving an occupational allergic contact dermatitis on theExpand
Contact allergy to Disperse Blue 106 and Disperse Blue 124 in German and Austrian patients, 1995 to 1999
DB 106/124 are important allergens deserving close monitoring, and the use of a mix of DB 106 and DB 124 seems justified in view of the close chemical similarity of both compounds. Expand
Disperse blue dyes 106 and 124 are common causes of textile dermatitis and should serve as screening allergens for this condition.
  • M. Pratt, V. Taraska
  • Medicine
  • American journal of contact dermatitis : official journal of the American Contact Dermatitis Society
  • 2000
Textile dye allergy is more common than previously reported and the most frequent allergens are Disperse Blue 106 and 124, which are frequently found in the 100% acetate and 100% polyester liners of women's clothing. Expand
Current patch test results in consecutive patients with, and chemical analysis of, disperse blue (DB) 106, DB 124, and the mix of DB 106 and 124
The allergen content of previously and currently used DB 106 and 124 and a respective mix is examined, and the frequency of positive PT reactions to the DB 106/124 mix and to the single compounds in consecutive PT patients is examined. Expand
Patch testing with thin‐layer chromatograms of chamomile tea in patients allergic to sesquiterpene lactones
Patients with contact allergy to sesquiterpene lactones (SLs) are usually hypersensitive to Asteraceae plant products such as herbal teas and patch testing with thin‐layer chromatograms of German chamomile tea showed the presence of several allergens. Expand
Textile dye dermatitis
The study population was 3336 patients investigated for contact dermatitis in our department from 1987 to 1991. All were patch tested with the European standard series (Trolab). 159 were also testedExpand
Thresholds of contact sensitization from disperse dyes in textiles
It is made a precautionary statement that patch testing may bear the risk of inducing sensitization or eliciting allergies in recurrent patients, if the dose applied is significantly higher than that which can be expected to be a maximum dose from dye migration. Expand
Textile dye contact dermatitis in an allergic population
A 62-year-old woman presented with a 4-year history of palatal lesions related to the wearing of a plastic dental prosthesis, which revealed erythema and slight erosions of the palate. Expand
Manual of Contact Dermatitis
Fregert'sManual of Contact Dermatitisis packed with useful information and is highly recommended as a primer for those learning dermatology and as a brief refresher text for the practicing clinician.Expand