Patch clamping the outer mitochondrial membrane


Intact giant mitochondria isolated from the liver of mice fed a diet containing cuprizone were studied using patch microelectrodes. The current-voltage curves were nonlinear, suggesting the presence of voltage-sensitive channels. In the negative range of voltage, the channels appear to close with increasing magnitude of the voltage. The dependence of the… (More)
DOI: 10.1007/BF01869611


12 Figures and Tables

Cite this paper

@article{Tedeschi1987PatchCT, title={Patch clamping the outer mitochondrial membrane}, author={Henry Tedeschi and Carmen A. Mannella and Charles L. Bowman}, journal={The Journal of Membrane Biology}, year={1987}, volume={97}, pages={21-29} }