Patch-clamp recording in myenteric neurons of guinea pig small intestine.

  title={Patch-clamp recording in myenteric neurons of guinea pig small intestine.},
  author={Lesia V Baidan and Alexander V. Zholos and M. Shuba and Jackie D. Wood},
  journal={The American journal of physiology},
  volume={262 6 Pt 1},
The results of our research established the feasibility of applying patch-clamp methods in the study of the cellular neurophysiology of myenteric neurons enzymatically dissociated from adult guinea pig small intestine. Recording in current-clamp mode revealed two populations of neurons. One population discharged repetitively during depolarizing current pulses and displayed anodal-break excitation reminiscent of S/type 1 myenteric neurons. In the second population, spike discharge was limited to… CONTINUE READING