Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease.

Abstract

N onalcoholic fatty liver disease (NAFLD), first recognized 30 years ago as a significant cause of liver-related morbidity and mortality, is now the most common cause of liver disease. The prevalence of hepatic steatosis in the pediatric population is estimated to be 10% and may be as high as 38% among obese children. Two-thirds of children with NAFLD and… (More)
DOI: 10.1002/hep.23946

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