Past adult lead exposure is associated with longitudinal decline in cognitive function

@article{Schwartz2000PastAL,
  title={Past adult lead exposure is associated with longitudinal decline in cognitive function},
  author={Brian S. Schwartz and Walter F. Stewart and Karen I. Bolla and David Simon and K. Bandeen-Roche and B Gordon and Jonathan M. Links and Andrew C Todd},
  journal={Neurology},
  year={2000},
  volume={55},
  pages={1144 - 1150}
}
Objective: To determine whether adults with past exposure to neurotoxicants have progressive declines in cognitive function years after exposure has ceased, and whether tibia lead is a predictor of the magnitude of change. Methods: A total of 535 former organolead manufacturing workers with a mean age of 55.6 years, a mean duration of 16 years since last occupational lead exposure, and low blood lead levels at the first study visit and 118 controls were evaluated with neurobehavioral tests two… Expand
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Long-term cumulative lead exposure may be weakly associated with faster cognitive decline in community-dwelling women, at least in some cognitive domains. Expand
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Longitudinal analysis of the Korean and organolead cohort indicate that the effect of lead is persistent, and a significant proportion of what is considered to be "normal" age-related cognitive decline may be due to past exposure to neurotoxicants such as lead. Expand
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