Past, Present, and Future of Traumatic Brain Injury Research.

  title={Past, Present, and Future of Traumatic Brain Injury Research.},
  author={Gregory W J Hawryluk and Malcolm Ross Bullock},
  journal={Neurosurgery clinics of North America},
  volume={27 4},
Traumatic brain injury (TBI) is the greatest cause of death and severe disability in young adults; its incidence is increasing in the elderly and in the developing world. Outcome from severe TBI has improved dramatically as a result of advancements in trauma systems and supportive critical care, however we remain without a therapeutic which acts directly to attenuate brain injury. Recognition of secondary injury and its molecular mediators has raised hopes for such targeted treatments… CONTINUE READING
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