Passovoy factor deficiency in five Western Australian kindreds.

@article{Jackson1981PassovoyFD,
  title={Passovoy factor deficiency in five Western Australian kindreds.},
  author={James Mark Jackson and Lindsay. Marshall and Richard P Herrmann},
  journal={Pathology},
  year={1981},
  volume={13 3},
  pages={517-24}
}
Passovoy factor deficiency, a coagulation abnormality affecting the intrinsic coagulation system, was discovered in 5 Western Australian kindreds. The defect is inherited as an autosomal dominant and is associated with a clinical bleeding tendency characterized by easy bruising and undue blood loss following trauma such as dental extraction and tonsillectomy. Fresh frozen plasma appears to provide effective prophylaxis during surgery. The activated partial thromboplastin time (APTT) shows a… CONTINUE READING