Passively transferred Lambert-Eaton syndrome in mice receiving purified IgG.

@article{Kim1986PassivelyTL,
  title={Passively transferred Lambert-Eaton syndrome in mice receiving purified IgG.},
  author={Yong Il Kim},
  journal={Muscle & nerve},
  year={1986},
  volume={9 6},
  pages={523-30}
}
Purified IgG antibodies were prepared by ion-exchange chromatography from the plasma of a patient with nonneoplastic form of the Lambert-Eaton myasthenic syndrome (LES). The antibodies were injected into mice with daily doses of 0.15-10 mg for 20-22 days, following which the integrity of neuromuscular transmission was assessed in vitro in phrenic nerve… CONTINUE READING