Passive uptake in the small intestine and active uptake in the hindgut contribute to the highly efficient mineral metabolism of the common mole-rat, Cryptomys hottentotus.

Abstract

Cryptomys hottentotus has no access to dietary or endogenous sources of cholecalciferol (D3). Serum concentrations of calcifediol (25(OH)D3) were undetectable (< 5 ng/ml) and calcitriol (1,25(OH)2D3), although detectable in plasma, was at a low concentration (31.40 (SEM 3.06 pg/ml). Despite their naturally impoverished vitamin D status, these animals… (More)

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