Passive stiffness of isolated cardiac and skeletal myocytes in the hamster.

@article{Fish1984PassiveSO,
  title={Passive stiffness of isolated cardiac and skeletal myocytes in the hamster.},
  author={Durland Fish and Joseph Orenstein and Sharon Bloom},
  journal={Circulation research},
  year={1984},
  volume={54 3},
  pages={267-76}
}
Single cardiac myocytes and skeletal myocyte fragments, devoid of interstitial collagen but with intact glycocalyx, were prepared by mechanical disaggregation of hamster ventricular myocardium and caudal gracilis muscle, respectively. Passive stiffness was studied by examining the sarcomere length-tension relationship over the approximate Eulerian stress range of 0-20 mN/mm2 for cardiac myocytes and 0-120 mN/mm2 for skeletal myocytes. Creep and stress-relaxation became apparent only when cells… CONTINUE READING