Passerine MHC: genetic variation and disease resistance in the wild

@article{Westerdahl2007PasserineMG,
  title={Passerine MHC: genetic variation and disease resistance in the wild},
  author={Helena Westerdahl},
  journal={Journal of Ornithology},
  year={2007},
  volume={148},
  pages={469-477}
}
The passerine major histocompatibility complex (MHC) class I and IIB genes are different from those of the avian model species the chicken because passerines have (1) a larger number of MHC genes, (2) MHC genes with longer introns, and (3) MHC genes that are pseudogenes. Most passerine MHC genes are transcribed (coding), extremely variable and subject to balancing selection. The high genetic diversity of the MHC genes of passerines is most likely maintained by selection from a large number of… CONTINUE READING