Pasireotide for postoperative pancreatic fistula.

  title={Pasireotide for postoperative pancreatic fistula.},
  author={Peter J. Allen},
  journal={The New England journal of medicine},
  volume={370 21},
BACKGROUND Postoperative pancreatic fistula is a major contributor to complications and death associated with pancreatic resection. Pasireotide, a somatostatin analogue that has a longer half-life than octreotide and a broader binding profile, decreases pancreatic exocrine secretions and may prevent postoperative pancreatic fistula. METHODS We conducted a single-center, randomized, double-blind trial of perioperative subcutaneous pasireotide in patients undergoing either… CONTINUE READING