Parvoviruses: Small Does Not Mean Simple.

@article{Cotmore2014ParvovirusesSD,
  title={Parvoviruses: Small Does Not Mean Simple.},
  author={Susan F. Cotmore and Peter J Tattersall},
  journal={Annual review of virology},
  year={2014},
  volume={1 1},
  pages={517-37}
}
Parvoviruses are small, rugged, nonenveloped protein particles containing a linear, nonpermuted, single-stranded DNA genome of ∼5 kb. Their limited coding potential requires optimal adaptation to the environment of particular host cells, where entry is mediated by a variable program of capsid dynamics, ultimately leading to genome ejection from intact particles within the host nucleus. Genomes are amplified by a continuous unidirectional strand-displacement mechanism, a linear adaptation of… CONTINUE READING

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