Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus.

@article{Amexis2006ParvovirusBE,
  title={Parvovirus B19 empty capsids as antigen carriers for presentation of antigenic determinants of dengue 2 virus.},
  author={Georgios Amexis and Neal S. Young},
  journal={The Journal of infectious diseases},
  year={2006},
  volume={194 6},
  pages={790-4}
}
For the production of dengue-vaccine candidates, empty capsids, or virus-like particles (VLPs), of parvovirus B19 that carry dengue 2-specific epitopes were employed as antigen carriers. Two epitopes (comprising amino acids 352-368 and 386-397) of domain BIII of the envelope glycoprotein were chosen to produce recombinant B19 VLPs for immunization of BALB/c… CONTINUE READING