Parvovirus B19 as a possible causative agent of fulminant liver failure and associated aplastic anemia.

@article{Langnas1995ParvovirusBA,
  title={Parvovirus B19 as a possible causative agent of fulminant liver failure and associated aplastic anemia.},
  author={Alan N. Langnas and Rodney S. Markin and Mark S Cattral and Stanley J. Naides},
  journal={Hepatology},
  year={1995},
  volume={22 6},
  pages={1661-5}
}
We recently observed that more than one third of pediatric patients who presented with non-A, non-B fulminant liver failure (FLF) also developed aplastic anemia (AA) either before or shortly after liver transplantation. Factors involved in the suppression of bone marrow could be the same as those causing hepatic failure. We considered parvovirus B19 a candidate etiologic agent because of the known tropism of B19 for erythroid precursors. Archived liver and serum from six patients undergoing… CONTINUE READING

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