Parvalbumin and calbindin D-28 k immunoreactivity in dorsal root ganglia in acquired immunodeficiency syndrome.

@article{Nagano1996ParvalbuminAC,
  title={Parvalbumin and calbindin D-28 k immunoreactivity in dorsal root ganglia in acquired immunodeficiency syndrome.},
  author={Isao Nagano and Paul Shapshak and Mitsuhiro Yoshioka and Ke Qin Xin and Seika Nakamura and Walter G. Bradley},
  journal={Neuropathology and applied neurobiology},
  year={1996},
  volume={22 4},
  pages={293-301}
}
Various degrees of neuronal degeneration have been found in lumbosacral dorsal root ganglia of patients with acquired immunodeficiency syndrome (AIDS). To characterize the subpopulations of primary sensory neurons affected in AIDS, we immunostained dorsal root ganglion tissues from 11 AIDS patients and six controls using antibodies to the calcium binding proteins, parvalbumin and calbindin D-28 k. In controls, the proportion of neurons containing parvalbumin and calbindin was 18.0% and 22.4… CONTINUE READING

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