Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle.

@article{Kimura2006ParturitionAH,
  title={Parturition and hypocalcemia blunts calcium signals in immune cells of dairy cattle.},
  author={Kayoko Kimura and Timothy A. Reinhardt and Jesse P. Goff},
  journal={Journal of dairy science},
  year={2006},
  volume={89 7},
  pages={2588-95}
}
The stress of parturition in the dairy cow is associated with increased susceptibility to infectious disease. During the periparturient period the demands for calcium are increased; these increased demands for calcium can result in subclinical or clinical hypocalcemia. Periparturient cows also experience significant immune suppression. Because intracellular calcium signaling is a key early feature in immune cell activation, we have hypothesized that the increased demand for calcium in… CONTINUE READING