Partnership of PGC-1α and HNF4α in the Regulation of Lipoprotein Metabolism*

@article{Rhee2006PartnershipOP,
  title={Partnership of PGC-1$\alpha$ and HNF4$\alpha$ in the Regulation of Lipoprotein Metabolism*},
  author={J. Rhee and H. Ge and Wenli Yang and M. Fan and C. Handschin and M. Cooper and J. Lin and Cai Li and B. Spiegelman},
  journal={Journal of Biological Chemistry},
  year={2006},
  volume={281},
  pages={14683 - 14690}
}
Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a transcriptional coactivator involved in several aspects of energy metabolism. It is induced or activated under different stimuli in a highly tissue-specific manner and subsequently partners with certain transcription factors in those tissues to execute various biological programs. In the fasted liver, PGC-1α is induced and interacts with hepatocyte nuclear factor 4α (HNF4α) and other transcription factors to activate… Expand

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