Partitioning of pyrene-labeled phospho- and sphingolipids between ordered and disordered bilayer domains.

@article{Koivusalo2004PartitioningOP,
  title={Partitioning of pyrene-labeled phospho- and sphingolipids between ordered and disordered bilayer domains.},
  author={Mirkka Koivusalo and Joni K O Alvesalo and Jorma A. Virtanen and Pentti Somerharju},
  journal={Biophysical journal},
  year={2004},
  volume={86 2},
  pages={923-35}
}
Here we have studied how the length of the pyrene-labeled acyl chain (n) of a phosphatidylcholine, sphingomyelin, or galactosylceramide affects the partitioning of these lipids between 1), gel and fluid domains coexisting in bovine brain sphingomyelin (BB-SM) or BB-SM/spin-labeled phosphatidylcholine (PC) bilayers or 2), between liquid-disordered and liquid-ordered domains in BB-SM/spin-labeled PC/cholesterol bilayers. The partitioning behavior was deduced either from modeling of pyrene excimer… CONTINUE READING