Partitioning of lung tissue response and inhomogeneous airway constriction at the airway opening.

@article{Suki1997PartitioningOL,
  title={Partitioning of lung tissue response and inhomogeneous airway constriction at the airway opening.},
  author={B{\'e}la Suki and Huichin Yuan and Qin Zhang and Kenneth R. Lutchen},
  journal={Journal of applied physiology},
  year={1997},
  volume={82 4},
  pages={
          1349-59
        }
}
During a bronchial challenge, much of the observed response of lung tissues is an artifactual consequence of inhomogeneous airway constriction. Inhomogeneities, in the sense of time constant inequalities, are an inherently linear phenomenon. Conversely, if lung tissues respond to a bronchoagonist, they become more nonlinear. On the basis of these distinct responses, we present an approach to separate real tissue changes from airway inhomogeneities. We developed a lung model that includes airway… CONTINUE READING

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