Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.

@article{Ibarguren2013PartitioningOL,
  title={Partitioning of liquid-ordered/liquid-disordered membrane microdomains induced by the fluidifying effect of 2-hydroxylated fatty acid derivatives.},
  author={Maitane Ibarguren and David J. L{\'o}pez and Josex0301 A. Encinar and Jos{\'e} Manuel Gonz{\'a}lez-Ros and Xavier Busquets and Pablo V. Escrib{\'a}},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1828 11},
  pages={2553-63}
}
Cellular functions are usually associated with the activity of proteins and nucleic acids. Recent studies have shown that lipids modulate the localization and activity of key membrane-associated signal transduction proteins, thus regulating the cell's physiology. Membrane Lipid Therapy aims to reverse cell dysfunctions (i.e., diseases) by modulating the activity of membrane signaling proteins through regulation of the lipid bilayer structure. The present work shows the ability of a series of 2… CONTINUE READING