Particulate Air Pollution, Blood Mitochondrial DNA Copy Number, and Telomere Length in Mothers in the First Trimester of Pregnancy: Effects on Fetal Growth

@inproceedings{Iodice2018ParticulateAP,
  title={Particulate Air Pollution, Blood Mitochondrial DNA Copy Number, and Telomere Length in Mothers in the First Trimester of Pregnancy: Effects on Fetal Growth},
  author={Silvia Iodice and Migena Hoxha and Luca Ferrari and Ilma Floriana Carbone and Claudio Anceschi and Michele Miragoli and Angela Cecilia Pesatori and Nicola Persico and Valentina Bollati},
  booktitle={Oxidative medicine and cellular longevity},
  year={2018}
}
Growing evidences have shown that particulate matter (PM) exposures during pregnancy are associated with impaired fetal development and adverse birth outcomes, possibly as a result of an exaggerated systemic oxidative stress and inflammation. Telomere length (TL) is strongly linked to biological age and is impacted by oxidative stress. We hypothesized that PM exposure during different time windows in the first trimester of pregnancy influences both mitochondrial DNA copy number (mtDNAcn), an… CONTINUE READING
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