Particles Resembling Papova Viruses in Human Cerebral Demyelinating Disease

@article{Rhein1965ParticlesRP,
  title={Particles Resembling Papova Viruses in Human Cerebral Demyelinating Disease},
  author={G. Z. Zu Rhein and Shi-Ming Chou},
  journal={Science},
  year={1965},
  volume={148},
  pages={1477 - 1479}
}
  • G. Z. Zu Rhein, Shi-Ming Chou
  • Published 1965
  • Biology, Medicine
  • Science
  • Degenerated brain tissue obtained from a deceased patient who had progressive multifocal leukoencephalopathy had been fixed in formalin prior to processing for electron microscopy. In ultrathin sections virus-like particles resembling papova virions were frequently observed in glial nuclei. Correlation with light-microscopy findings suggests that demyelination resulted from the cytocidal effect of the virus on oligodendroglia. 
    JC Papovavirus in progressive multifocal leukoencephalopathy.
    • 104

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 17 REFERENCES