Particle size tailoring of ursolic acid nanosuspensions for improved anticancer activity by controlled antisolvent precipitation.

@article{Wang2015ParticleST,
  title={Particle size tailoring of ursolic acid nanosuspensions for improved anticancer activity by controlled antisolvent precipitation.},
  author={Yancai Wang and Ju Min Song and Shing Fung Chow and Albert Hee Lum Chow and Ying Zheng},
  journal={International journal of pharmaceutics},
  year={2015},
  volume={494 1},
  pages={479-89}
}
The present study was aimed at tailoring the particle size of ursolic acid (UA) nanosuspension for improved anticancer activity. UA nanosuspensions were prepared by antisolvent precipitation using a four-stream multi-inlet vortex mixer (MIVM) under defined conditions of varying solvent composition, drug feeding concentration or stream flow rate. The… CONTINUE READING