Particle and nanoparticle interactions with fibrinogen: the importance of aggregation in nanotoxicology.

Ingested, inhaled or injected particles come into contact with biological fluids containing polymers, such as the protein fibrinogen. We studied interactions between well-characterized submicron particles or nanoparticles (NPs) and human fibrinogen. In vitro aggregation and zeta potential measurements of different sized and functionalized polystyrene… CONTINUE READING