Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice.

@article{Valverde1994ParticipationOO,
  title={Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice.},
  author={Olga Valverde and Juan Antonio Mic{\'o} and Rafa{\"e}l Maldonado and M L Mellado and Juan Gibert-Rahola},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={1994},
  volume={18 6},
  pages={1073-92}
}
1. Various clinical and experimental reports indicate that tricyclic antidepressant drugs are specially useful in the treatment of chronic and acute pain conditions. The present work was aimed to study the mechanisms implicated in the antinociceptive response induced by these antidepressants on different experimental models of pain in mice, and particularly the role played by noradrenergic, serotonergic and opioidergic influences. 2. Electrical stimulation of the tail and formalin tests were… CONTINUE READING
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