Participation of cytochrome P-450 in the steroid 17alpha-hydroxylase of testis microsomes.

Abstract

The effect of metyrapone on the activity of the steroid 17alpha-hydroxylase from rat testis was evaluated. A competitive pattern of inhibition was observed after analysis of data using a least mean squares computer analysis. The substrate for the hydroxylase induced a Type I difference spectrum in an active suspension of Triton treated microsomes. The… (More)

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@article{Betz1975ParticipationOC, title={Participation of cytochrome P-450 in the steroid 17alpha-hydroxylase of testis microsomes.}, author={G. Betz and Pei-Shan Tsai and R G Weakley}, journal={Steroids}, year={1975}, volume={25 6}, pages={791-8} }