Participation of Ca2(+)-activated K+ channels in electrical activity of canine gastric smooth muscle.

@article{Carl1990ParticipationOC,
  title={Participation of Ca2(+)-activated K+ channels in electrical activity of canine gastric smooth muscle.},
  author={Angelika Carl and Noel G. McHale and Nelson G. Publicover and Kenton M. Sanders},
  journal={The Journal of physiology},
  year={1990},
  volume={429},
  pages={205-21}
}
1. The hypothesis that Ca2(+)-activated K+ channels participate in the repolarization of electrical slow waves was tested in isolated cells and intact muscles of the canine gastric antrum. 2. Freshly dispersed cells from the gastric antrum liberally express large conductance channels that were characterized as Ca2(+)-activated K+ channels by several criteria. 3. Mean slope conductance of these channels in symmetrical 140 mM-KCl solutions was 265 +/- 25 pS and reversal potential was 1.3 +/- 3.3… CONTINUE READING

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