Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans.

@article{Layer1985PartiallyPW,
  title={Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans.},
  author={Peter Layer and Gordon Lawrence Carlson and Eugene P Dimagno},
  journal={Gastroenterology},
  year={1985},
  volume={88 6},
  pages={1895-902}
}
Whether commercial, bean-derived alpha-amylase inhibitor preparations failed to decrease starch digestion in humans because of insufficient antiamylase activity, destruction by gastrointestinal secretions, or decreased activity in the presence of starch is unknown. We used a simple partial purification procedure to markedly concentrate the inhibitor (sixfold to eightfold by total protein content, and 30-40-fold by dry weight). Compared with a commercial preparation and crude bean extract, this… CONTINUE READING
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