Partial volume effects on arterial input functions: shape and amplitude distortions and their correction.

@article{Osch2005PartialVE,
  title={Partial volume effects on arterial input functions: shape and amplitude distortions and their correction.},
  author={Matthias J. P. van Osch and J van der Grond and Chris J. G. Bakker},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2005},
  volume={22 6},
  pages={704-9}
}
For quantification of perfusion values from a bolus-tracking MRI experiment, the measurement of an arterial input function (AIF) is necessary. Gradient-echo (GE) sequences are commonly used for this type of experiment because they offer a high signal-to-noise ratio (SNR) and the potential to quantify the concentration of contrast agent. Measurements of calibration curves for Gd-DTPA in human blood have shown a quadratic relation between the DeltaR(2)* and the concentration of contrast agent… CONTINUE READING

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