Partial versus maximal forced exhalations in COPD: enhanced signal detection for novel therapies.

Abstract

BACKGROUND Evaluation of novel compounds for COPD often relies on FEV1 for signal detection. Partial forced exhalations from end-tidal inspiration (PEFV) might complement FEV1 in identifying such a signal. We examined the prevalence of bronchodilator response (BDR) using PEFV and FEV1 in patients with COPD. METHODS 110 consecutive COPD patients were… (More)
DOI: 10.1016/j.pupt.2014.03.004

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