Partial trisomy 4q: Two cases resulting from a familial translocation t(4;18)(q27;p11)


Partial trisomy of the long arm of chromosome 4 was observed in two related patients, a child aged 2 years and a woman aged 42. Cytogenetic investigation revealed that their chromosome anomalies were due to segregation of a familial balanced translocation t(4;18)(q27;p11). Some clinical and cytogenetic considerations are noted. 
DOI: 10.1007/BF00284601


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