Partial therapeutic response to Rituximab for the treatment of chronic alloantibody mediated rejection of kidney allografts.

@article{Smith2012PartialTR,
  title={Partial therapeutic response to Rituximab for the treatment of chronic alloantibody mediated rejection of kidney allografts.},
  author={Rex Neal Smith and Fahim A Malik and Nelson Goes and Alton Brad Farris and Emmanuel Zorn and Susan L. Saidman and Nina Tolkoff-Rubin and Sonika Puri and Waichi Wong},
  journal={Transplant immunology},
  year={2012},
  volume={27 2-3},
  pages={107-13}
}
BACKGROUND AND OBJECTIVES Chronic rejection leads to kidney allograft failure and develops in many kidney transplant recipients. One cause of chronic rejection, chronic antibody mediated rejection (CAMR), is attributed to alloantibodies. Maintenance immunosuppression including prednisone, mycophenolate mofetil (MMF) and calcineurin inhibitors may limit alloantibody production in some patients, but many maintain or develop alloantibody production, leading to CAMR. Therefore, no efficacious… CONTINUE READING
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