Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease.

@article{Papi2000PartialRO,
  title={Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease.},
  author={Alberto Papi and Micaela Romagnoli and Simonetta Baraldo and Fausto Braccioni and Ippolito Guzzinati and Marina Saetta and Adalberto Ciaccia and Leonardo M Fabbri},
  journal={American journal of respiratory and critical care medicine},
  year={2000},
  volume={162 5},
  pages={1773-7}
}
We investigated the relationship between the reversibility of airflow limitation, the concentration of nitric oxide (NO) in exhaled air, and the inflammatory cells in the sputum of patients with stable chronic obstructive pulmonary disease (COPD). We examined nine normal healthy control subjects and 20 nonatopic patients with COPD. Ten patients had no reversibility of airflow limitation (increase in FEV(1) of < 12% and < 200 ml after 200 microg of inhaled salbutamol), and 10 patients had… CONTINUE READING