Partial purification and characterization of the bone resorption factor fromActinomyces viscosus

@article{Hausmann2006PartialPA,
  title={Partial purification and characterization of the bone resorption factor fromActinomyces viscosus},
  author={Ernest Hausmann and Bala C Nair and Kenneth W. Knox and Kevin W. Broady and Anthony J. Wicken and M J Brown and R. Dziak},
  journal={Calcified Tissue International},
  year={2006},
  volume={34},
  pages={49-53}
}
SummaryThe bone resorptive factor and amphipathic antigen (AcA) previously identified by us in preparations fromActinomyces viscosus have been partially purified, characterized chemically, and compared. They elute at the same location on chromatography with Ac 22. The fatty acid composition of AcA and the bone resorptive factor is the same. Some differences in carbohydrate composition are observed. TheActinomyces factor does not affect calcium influx or cyclic AMP in isolated bone cells… 
3 Citations

Macrophage Activation and Cytotoxicity by Oral Bacteria

TLDR
The LDH level in the culture supernatant was markedly increased by the addition of cell components of Veillonella parvula, suggesting cytotoxicity of the bacteria.

Bone resorption in periodontal diseases: role of bacterial factors.

Summary. The bone resorbing activity of lipopolysaccharides from oral bacteria has been investigated in vitro. Further, the resorbing activity appeared to be reduced by serum, except in the case of

References

SHOWING 1-10 OF 30 REFERENCES

Structural Requirements for Bone Resorption by Endotoxin and Lipoteichoic Acid

TLDR
Lipoteichoic acid was compared with a preparation free of fatty acids to determine whether LPS-stimulated bone resorption is mediated by prostaglandin synthesis in bone and to obtain information on the portion of the endotoxin and lipote Jerichoic acid molecules necessary for their bone Resorptive effect.

Effects of lipopolysaccharides on bone resorption in tissue culture

TLDR
There is no relationship between the ability of lipopolysaccharides to stimulate the resorption of bone and pyrogenicity or their ability to neutralize antibody.

Serological properties of the wall and membrane teichoic acids from Lactobacillus helveticus NCIB 8025.

TLDR
Both wall and membrane teichoic acids from Lactobacillus helveticus NCIB 8025 are glycerol phosphate polymers partially substituted with α-D-glucosyl residues, primarily responsible for the serological specificity of the membrane antigen.

Endotoxin: Stimulation of Bone Resorption in Tissue Culture

TLDR
Endotoxins may play a role in the bone loss characteristic of human periodontal disease and are inhibited by serum and dependent upon the presence of albumin.

Studies on the group F antigen of lactobacilli: isolation of a teichoic acid-lipid complex from Lactobacillus fermenti NCTC 6991.

TLDR
Membrane glycerol teichoic acid has been extracted from Lactobacillus fermenti NCTC 6991 by two different procedures using Phenol extraction and Trichloracetic acid extraction, which resulted in degraded lipoteichoic Acid and free te Jerichoic acid chains.

New cellular and extracellular amphipathic antigen from Actinomyces viscosus NY1

A new type of amphipathic antigen was isolated from culture supernatants and cells of Actinomyces viscosus NY1 and partially characterized as a fatty acid-substituted heteropolysaccharide. Similar

Isolation of lipopolysaccharide endotoxin.

Studies on the group F antigen of lactobacilli: detection of antibodies by haemagglutination.

TLDR
Teichoic acid-lipid complexes from Lactobacillus fermenti NCTC 6991 absorb to normal sheep red blood cells and the significance of the absorption by intact bacterial cells is discussed.

Effect of phosphate, calcium and magnesium on bone resorption and hormonal responses in tissue culture.

TLDR
Increasing the phosphate concentration of the medium over the range of 0.25 to 4M produced a decreased release of calcium from bone, particularly in response to parathyroid hormone, demonstrating that active resorption was inhibited.