Partial purification and characterization of DNA from the human X chromosome.

@article{Schmeckpeper1979PartialPA,
  title={Partial purification and characterization of DNA from the human X chromosome.},
  author={Barbara J Schmeckpeper and Kirby D. Smith and B P Dorman and Frank H. Ruddle and C Conover Talbot},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1979},
  volume={76 12},
  pages={6525-8}
}
Human X chromosome DNA was partially purified from a mouse-human hybrid cell line containing a single human chromosome, the X. Enrichment of such DNA was accomplished by two sequential reassociations of radiolabeled hybrid cell DNA with large excesses of mouse DNA. Unreassociated hybrid cell DNA was used as a probe for human X chromosome sequences. The… CONTINUE READING